Handshake with two different clocks

In reply to foxtrot:

…but it’s a vacuous pass even when ack rises after say 4 or 6 clk2 cycles.

Vacuity occurs only if the antecedent $rose(req)==0.
Keep in mind that at every clocking event (i.e., the @(negedge clk1)) you have an attempt at the property, and if in the cycles af$ter the successful $rose(req) you have no more rose, then those attempts are vacuous. Maybe what you see are those vacuous threads.
However, the attempt with a successful $rose(req) can finish in one of the possible ways:
PASS, FAIL, INCOMPLETE (if at end of simulation ack never occurred).
Try the following


ap_reqack: assert property(@(negedge clk1) $rose(req) |-> 
          @(posedge clk2) !ack[*4:$] ##1 ack) $display("%t PASS", $realtime);
          else $display("%t FAIL", $realtime); 

Ben Cohen
http://www.systemverilog.us/ ben@systemverilog.us
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** SVA Handbook 4th Edition, 2016 ISBN 978-1518681448

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