Toggle a force signal inside OVM sequence

In reply to tejasakulu:

Another force on a signal replaces an existing force—there’s no need to release it first.

Also, there’s no need to force to a literal constant. You can do

bit vr_reg;
initial force DUT_TOP_INST.vt =vr_reg;
initial begin
 #300ns;
 vr_reg = ~vr_reg;
end

That way you can set up a driver to modify the value of vr_reg directly.