In reply to Yeptho:
interface my_itf(input clk1,clk2);
wire signal;
clocking cb1 @(posedge clk1);
output signal;
endclocking
clocking cb2 @(posedge clk2);
output signal;
endclocking
endinterface
Assuming you have a virtual interface handle vif, you would drive the signal with either
vif.cb1.signal <= something;
// or
vif.cb2.signal <= something;