In reply to GC:
May be I would like to understand the question a bit more ..
i. Do you mean you are bringing up the setup now for RTL or
ii. Do you have to port the setup from one vendor to another?
In case i) you have to understand that the DV setup you are going to bring up is going to be vendor specific and if you are compliant to the LRM development porting should be straightforward by searching and replacing the options of one vendor with another...
In case ii) If the TB is already built without keeping vendor independence in mind, you may run into some issues ..